This refers to how an allosteric modulator affects signaling for a specific orthosteric agonist. For instance, an allosteric modulator may perhaps change THC signaling, although not endogenous cannabinoid signaling. An important prospective endogenous damaging allosteric modulator for CB1 will be the steroid hormone, pregnenolone [40–42]. Some (however not all [forty https://insurance-claims-assistan42211.dreamyblogs.com/33203202/cannabis-strains-an-overview