Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors in the central nervous process, conolidine modulates alternate molecular targets. A Science Innovations analyze found that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://conolidinewheretobuy91234.loginblogin.com/46658446/what-does-alternative-natural-pain-relief-to-replace-traditional-painkillers-mean